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Transforming medical research: Empowering researchers with Absolute Q

Product Engineering
Digital Experience
Digital Application Development
Product Design

Key challenges

01

Combinati's hardware instruments required a sophisticated software solution to enable efficient Data Processing and Analysis, ensuring researchers could work seamlessly with the dPCR, short for Digital PCR, a cutting-edge molecular biology technique used to quantify and amplify nucleic acid, such as DNA or RNA, results in a sample

02

The development of the software was aimed at democratizing Digital PCR, empowering researchers worldwide with accessible and impactful disease-driven biomarker tracking and healthcare information

03

Developing a cutting-edge dPCR platform that drastically reduced processing time by ~90 minutes while maintaining high levels of accuracy and precision in analysis

Client in spotlight

Combinati believes simplicity shouldn’t require sacrificing robustness, quality or rigor – in fact, it should enable it. The customer’s easy-to-use Digital PCR platform offers absolute quantification to track disease-relevant biomarkers over time with high accuracy and precision. Comprised of a single instrument and a single consumable, the core microfluidic technology enables the partitioning of samples with minimal waste. Combined with the ability to robustly reject false positives and easily adapt traditional qPCR assays, Combinati aimed to democratize Digital PCR for researchers all over the world.

Unlocking Digital Success

Ideation
Identifying the need for a sophisticated software solution that seamlessly integrated with the hardware instruments to enable scientists to analyze and work with data efficiently
Our approach
Kellton embarked on an 18-month journey with Combinati, dedicating a team of 3-7 experts at any given time, to design and build the Absolute Q application from scratch
Outcomes
The Absolute Q software component empowered scientists and researchers with a game-changing dPCR platform significantly reducing processing time (~ 90 minutes) without compromising analysis accuracy

Project outcomes

01
Successful development of the software component for Combinati's Absolute Q platform, enabling efficient Data Processing and Analysis
02
Significantly reduces processing time (~90 minutes) compared to market leaders while maintaining high accuracy and precision in analysis, leading to improved lab throughput and accelerated research in critical medical fields like Infectious Disease and Oncology
03
Contributed to the fight against COVID-19 by offering sensitive detection of viral RNA targets, proving to be a more sensitive method of SARS-CoV-2 detection, and supporting community spread tracking through wastewater screening capabilities
Success Stories

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